Effect of intrauterine infusion of ceftiofur on uterine health and fertility in dairy cows

Uterine diseases such as metritis and endometritis are highly prevalent in high-producing dairy cows and are associated with decreased pregnancy per AI, extended interval to pregnancy, increased culling, and conomic losses (Bartlett et al., 1986; Sheldon and Dobson, 2004; Gilbert et al., 2005). In addition to clinical uterine disease, subclinical endometritis, which is characterized by increased proportion of olymorphonuclear eutrophils in uterine cytology, has a major detrimental effect on fertility of dairy cows (Kasimanickam et al., 2004; Gilbert et al., 2005; Rutigliano et al., 2008). Cows diagnosed with retained placenta and metritis early ostpartum have twice the odds of developing subclinical endometritis after 30 DIM (Rutigliano et al., 2008).

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